ClawCures

An AI Agent for Drug Discovery

ClawCures is an experimental AI agent built on OpenClaw. It plans and runs drug discovery research, starting with severe and neglected diseases and looking for treatment approaches supported by the biology.

24/7 Autonomous Operation
All Diseases Targeted
Full-Stack Biotech Coverage
Open Source AgentCures Refua

Find cures for all diseases by prioritizing the highest-burden conditions and researching the best drug design strategies for each.

The default ClawCures prompt

What Is ClawCures?

ClawCures can work on a specific disease or research question. Its default objective is broader: prioritize severe and neglected diseases, then investigate possible treatments.

The agent reviews scientific literature, runs machine-learning models, designs and ranks compounds, coordinates experiments with contract research organizations (CROs), and drafts regulatory documents such as IND applications.

The code is open source, so you can inspect how it works and try it with your own research objectives.

Key Capabilities

  • Reads and synthesizes scientific literature
  • Runs ML models for drug design
  • Designs de novo antibodies with optimized properties
  • Coordinates CRO wet-lab experiments
  • Prepares IND regulatory documentation
  • Prioritizes highest-burden diseases

See It In Action

Start ClawCures with one command. Give it a disease to investigate, or use its default objective.

$ clawcures run

🦞 Initializing ClawCures autonomous agent...

📋 Loading default objective: cure all human disease

🔬 Ranking disease portfolio by global burden...

🧬 Generating therapeutic hypotheses...

⚡ Planning via OpenClaw gateway...

✅ Campaign running. Iteration 1 of ∞

How It Works

ClawCures separates planning from execution. OpenClaw generates strategic plans, while Refua MCP executes typed scientific tools in an auditable workflow.

Define Objective

Set a disease target or let ClawCures default to its all-disease mission.

Literature Synthesis

The agent reviews scientific papers and compares possible treatment strategies.

Compound Design

ML models design and evaluate small molecules, peptides, and new antibodies.

Lab Coordination

ClawCures coordinates CRO wet-lab experiments to validate promising candidates.

Regulatory Prep

Draft IND sections and supporting documents for review.

From Research to Documentation

ClawCures connects computational modeling, lab coordination, and regulatory document preparation.

📚

Literature Review

Reads and indexes scientific papers to identify treatment ideas and the evidence behind them.

🧠

ML-Powered Design

Runs machine-learning models to design and score compounds, predict binding affinity, and optimize drug-likeness.

🧬

De Novo Antibodies

Designs antibody candidates computationally, considering predicted binding, stability, and suitability for development.

🔬

Wet-Lab Coordination

Connects with CRO partners to commission lab experiments and track their results.

📋

Regulatory Documentation

Drafts IND applications, study reports, and regulatory dossiers from the research record.

🌍

Disease Prioritization

Ranks diseases by severity and neglect to help choose where to focus research.

Part of the AgentCures Ecosystem

ClawCures is part of Refua, the AgentCures collection of open-source tools for drug discovery.

It brings together Amiti for molecular screening, Refua MCP for scientific tools, and OpenClaw for planning, alongside tools for clinical simulation, regulatory evidence, and data.

You can add integrations to connect the agent with the services your research team uses.

Ecosystem Integration

  • Amiti molecular embedding model
  • Refua MCP scientific tool server
  • OpenClaw planning engine
  • Clinical trial design tools
  • Regulatory dossier generation
  • Extensible integration framework

Join the Mission

Try ClawCures with a research question, inspect its plans, and help improve the tools. The project is open source and welcomes contributions.